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BCNU also used in implantable wafers Temozolomide Myelosuppression, noncumulative The most commonly used agent in gliomas; relatively low toxicity profile (16,22,23) (20,24) Procarbazine DNA alkylation Topoisomerase I inhibition Differentiating agent PKC inhibition Interaction with MAO inhibitors and tyramine-rich foods Used mostly in PCV combination regimen Irinotecan Diarrhea can be severe Chelitis, teratogenic Deep vein thrombosis Marked effect on serum levels by P450-active AEDs (2527) (28,29) (3034) Isotretinoin (cis retinoic acid) Well tolerated, mainly cytostatic Tamoxifen Abbr:MAO, monoamine oxidase; AED, antiepileptic drug; PKC, protein kinase C.

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r2cos 1 (a) e 2 (b) Ellipse (c) x4 (d) The vertices are 1 1 2 cos 1 1 2 cos 44 3 ,0 and (4, )( 4,0)so the center is 3 ,0. References and further reading Control Engineering (Editorial) (April 1998), pp.

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(1986): A low voltage diathermy loop for taking cervical biopsies: a qualitative comparison with punch biopsy forceps. Over-expression of CNPase in transgenic mice perturbs myelin formation and creates aberrant OL membrane expan- sion. As we argued right at the beginning of Section 10-1, closed colonies of monkeys.

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